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Prior Scientific

Prior Scientific

Experts in Precision Positioning and Microscope Automation

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  • Imaging Components
    • Motorized Stages
    • Focus Mechanisms
    • Laser Autofocus
    • Filter Wheels, Turrets & Shutters
    • Controllers & Joysticks
    • Robotic Sample Loaders
    • Physiology Platforms
    • Motorized Vertical Stages
  • Microscope Automation
    • Evident Olympus Microscope Automation
    • Nikon Microscope Automation
    • Leica Microscope Automation
    • Zeiss Microscope Automation
    • Automated Custom Imaging Systems
    • Other Microscope Brands
  • Nanopositioning Devices
  • Vibration Control
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Home » Imaging Components

Microscope Laser Autofocus

Our hardware autofocus system provides real-time focus control for most infinity-corrected optical systems and is suitable for both life science and industrial samples.  The system can track reflective sample surfaces directly or be used to maintain focus on non-reflective tissues or cells by offsetting from a coverslip or other reflective surface.

Using a combination of advanced optics and an intelligent microprocessor, the hardware laser autofocus maintains focus by interfacing with stepper motor and piezo devices and creating a feedback loop to track the sample.

It is suitable for use with numerous microscopy techniques, including fluorescence, and even high-resolution advanced methods such as TIRF are also supported. The autofocus can significantly decrease imaging times, enhance microscope ease of use, or support time-lapse applications.

The system is also adaptable – optics can be swapped to support imaging outside visible light wavelengths, integration with other motor types can be facilitated, and output signals taken directly for interface with external devices.

The laser autofocus is compatible with a wide range of options for all major brands of microscope, including Leica, Zeiss, Olympus and Nikon. For integrating with a Nikon or an Olympus microscope see our automation guides:  

Nikon Automation Guide  

Evident/Olympus Automation Guide  

Or contact us to discuss your specific brand or model of microscope.

OEM and Customization Service

We offer a full customization and consultation service for our OEM customers. We partner with you to quickly prototype, test and bring new imaging instrumentation to market. Learn more

 

 

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2  Products
PureFocus690 hardware laser autofocus system on a grey background.

PureFocus™690 Laser Autofocus System

Hardware Laser Autofocus for Raman and IR Microscopy

Learn More
PureFocus850 Laser autofocus module for automated imaging.

PureFocus™850 Laser Autofocus System

Hardware Laser Autofocus For Industrial And Life Science Microscopy

Learn More

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    Prior Scientific Instruments Ltd.
    Units 3-4 Fielding Industrial Estate
    Wilbraham Road, Fulbourn
    Cambridge, CB21 5ET, UK

    inquiries@prior.com
    +44 (0)1223 881711

    Prior Scientific Inc.
    80 Reservoir Park Drive
    Rockland, MA. 02370
    U.S.A.

    info@prior.com
    +1 781 878 8442

    Prior Scientific Instruments GmbH
    Maria-Pawlowna-Str. 4
    07743 Jena
    Germany

    jena@prior.com
    +49 (0)3641 242 010

    Prior Scientific KK
    Kayabacho 3rd Nagaoka Bldg 10F,
    2-7-10, Nihonbashi Kayabacho
    Chuo-Ku, Tokyo 103-0025, Japan

    info-japan@prior.com
    +81 (0)3 5652 8831

    Prior Scientific Instruments (Suzhou) Ltd.
    Room 118, Meilihua Hemu Park,
    No. 393 Suhong Middle Road,
    Suzhou Industrial Park,
    Suzhou, 215000, China

    info-china@prior.com
    +86 (0)512 6617 5866

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