{"id":5048,"date":"2026-04-21T12:00:00","date_gmt":"2026-04-21T12:00:00","guid":{"rendered":"https:\/\/gk5l0g06kd.onrocket.site\/blog\/high-speed-fluorescence-imaging-for-automated-microscopy-systems\/"},"modified":"2026-09-11T19:37:03","modified_gmt":"2026-09-11T19:37:03","slug":"high-speed-fluorescence-imaging-for-automated-microscopy-systems","status":"publish","type":"blog","link":"https:\/\/www.prior.com\/us\/blog\/high-speed-fluorescence-imaging-for-automated-microscopy-systems\/","title":{"rendered":"HF108B Filter Wheel: High\u2011Speed Fluorescence Imaging for Automated Microscopy Systems"},"content":{"rendered":"
Home<\/a><\/span> \u00bb Blog<\/a><\/span> \u00bb HF108B Filter Wheel: High\u2011Speed Fluorescence Imaging for Automated Microscopy Systems<\/span><\/span><\/div>\n\n
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HF108B Filter Wheel: High\u2011Speed Fluorescence Imaging for Automated Microscopy Systems<\/h1>\n\n\n\n

21.04.26<\/p>\n\n\n\n

Modern fluorescence imaging demands speed, stability, and compatibility with increasingly large fields of view. Prior Scientific’s HF108B filter wheel<\/a> has been engineered to meet these requirements head\u2011on — delivering rapid filter switching, outstanding optical performance, and an ultra\u2011thin profile suitable for commercial microscopes, confocal units, and OEM imaging platforms.<\/p>\n\n\n\n

Designed for Speed: Achieve sub\u201138\u202fms filter switching for fast fluorescence imaging<\/h2>\n\n\n\n

Most fast fluorescence imaging<\/a> techniques rely on rapid, reliable movement between filter positions. The HF108B achieves filter-switching times under 38 ms, enabling users to capture dynamic processes with greater temporal resolution and significantly lower inter-channel delay. This performance is ideal for high\u2011throughput applications, live\u2011cell imaging, and any workflow where minimizing photobleaching and phototoxicity is critical. With modern imaging systems increasingly optimized for larger fields of view, the HF108B keeps pace by supporting 32 mm diameter filters to ensure maximum clarity and detection efficiency across large sensors. <\/p>\n\n\n\n

With eight filter positions, the HF108B gives users the freedom to expand their setup — expanding the wavelength range of their light source or incorporating novel infrared fluorescent probes without reconfiguring hardware. <\/p>\n\n\n\n

Transform Your Imaging Workflow<\/h2>\n\n\n\n

Faster filter switching doesn’t just improve image acquisition speed: it transforms entire experimental workflows.<\/p>\n\n\n\n

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  • Higher-throughput screening becomes possible because fluorescence channels can be captured more quickly.<\/li>\r\n\t
  • Reduced exposure of live cells to light avoids photobleaching during sensitive experiments.<\/li>\r\n\t
  • By moving from a motorized filter turret to an emission filter wheel, researchers can reduce acquisition times by more than fivefold, enabling them to capture more data in less time. <\/li>\r\n<\/ul>\n\n\n\n

    Compatible with multiple camera adapters<\/h2>\n\n\n\n

    The HF108B can be configured with numerous common camera adapters:<\/p>\n\n\n\n

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    • C\u2011mount for standard microscopy cameras<\/li>\r\n\t
    • F\u2011mount to achieve the full field of view offered by modern microscopes<\/li>\r\n\t
    • TFL\u2011mount for a more stable connection with cameras using APS\u2011C format sensors <\/li>\r\n<\/ul>\n\n\n\n

      Adapters can be swapped easily, even after installation, allowing users to adapt their system quickly as their imaging requirements evolve.<\/p>\n\n\n\n

      Simple installation on upright or inverted microscopes<\/h2>\n\n\n\n

      The HF108B is engineered to make installation as straightforward as possible. It arrives pre-fitted with the correct adapter for the intended microscope, and it can be mounted on both upright and inverted configurations with ease. <\/p>\n\n\n\n

      Users simply position the wheel on the camera port and secure it in place. The system is designed to ensure the camera sits at the correct optical distance from the microscope without additional optics or spacers, reducing setup time and simplifying system integration. <\/p>\n\n\n\n